永利集团-永利国际-永利网址

    当前位置: 永利集团 >> 研究队伍

自动化研究所人才库

  • 姓名: 杜洋
  • 性别: 女
  • 职称: 研究员
  • 电子邮件: yang.du@ia.ac.cn
    简  历:
  • 单位地址:北京市中关村东路95号智能化大厦905室
    电话 :010-62611658-905
    传真 :010-62527995
    个人主页: http://people.ucas.ac.cn/~duyang

     

    工作经历:
    1.2017.11-至今,永利科学院自动化研究所,研究员
    2.2012.11-2017.10,永利科学院自动化研究所,副研究员
    3.2010.04-2012.10,美国德克萨斯州大学艾德森癌症研究中心,博士后
    4.2009.11-2010.03,美国德克萨斯州大学西南研究中心,博士后

     

    教育经历:
    1.2005.09-2009.10, 香港大学,博士
    2.2002.09-2005.07,大连医科大学,硕士
    3.1997.09-2002.07,大连医科大学,学士

     

    研究方向:
    1.医学分子成像
    2.医学图像处理与分析
    3.医学影像大数据分析

     

    代表性论著 (SCI):
    1.Du Y, Yang M, Wei W, Huynh HD, Herz J, Saghatelian A, Wan Y*(2012). Macrophage VLDL receptor promotes PAFAH secretion in mother's milk and suppresses systemic inflammation in nursing neonates. Nature Communications. 2012;3:1008. doi: 10.1038/ncomms2011. (2019 SCI: 11.878) 
    2.Yang Du#, Xiaoli Liu#, Qian Liang#, Xingjie Liang*, Jie Tian*(2019) Optimization of Magnetic Theranostic Agent for in vivo MPI/MRI-guided Magnetic Hyperthermia Therapy. Nano Letters. 2019 May 10. doi: 10.1021/acs.nanolett.9b00630. (2019 SCI: 12.279)
    3.Du Y#, Jiang Q#, Beziere N#, Song L, Zhang Q, Peng D, Chi C, Yang X, Guo H, Diot G, Ntziachristos V*, Ding B*, Tian J*(2016). Theranostic Gold Nanorod?DNA Origami Hybrids for Enhanced in vivo Optoacoustic Imaging and Photothermal Therapy. Advanced Materials. 2016 Dec;28(45):10000-10007. (2019 SCI: 25.809)
    4.Xiao-Li Liu#, Jianjun Zheng#, Wei Sun#, Yao Li, Yan Yun Wang, Ning Qiang Gong, Xiao Wei Ma1, Huan Zhang, Ling-Yun Zhao, Yang Du*, Hai-Ming Fan*, Jie Tian*, Xing-Jie Liang*(2019). Physiological-thermal Therapy Mediated by Magnetic Vortex Nanorings Potentiates Checkpoint Blockade Cancer Immunotherapy. ACS Nano. 2019 Accepted. (2017 SCI: 13.709)
    5.Zhang Q^, Jiang Q^, Li N, Dai L, Liu Q, Song L, Wang J, Li Y, Tian J, Ding B*, Du Y* (2014). DNA origami as an in vivo drug delivery vehicle for cancer therapy. ACS Nano. 2014 Jul 22;8(7):6633-43. (2019 SCI: 13.903)
    6.Jiang Q, Shi Y, Zhang Q, Li N, Zhan P, Song L, Dai L, Tian J, Du Y*, Cheng Z*, Ding B*. (2015). Self-assembled Gold DNA Nanoparticles for Cancer Theranostics. Small. 2015 Oct;11(38):5134-41. (2019 SCI: 10.856)
    7.Sun wei#, Yang Du#, Xiaolong Liang#, Yinhua Jin*, Jie Tian*, Jianjun Zheng* (2019), Chemo-photothermal synergistic therapy with nanoparticles guided by multimodal imaging in combination with checkpoint blockade for immunotherapy of breast cancer. Biomaterials. 23 June 2019, 119264. DOI: https://doi.org/10.1016/j.biomaterials.2019.119264. (2017 SCI: 10.273)
    8.Yang Du+, Xiaolong Liang+, Yuan Li+, Ting Sun, Huadan Xue, Zhengyu Jin*, Jie Tian*. Liposomal Nanohybrid Cerasomes Targeted to PD-L1 Enable Dual-Modality Imaging and Improve Antitumor Treatments (2017). Cancer Letters. 2018 Feb 1;414:230-238. (2019 SCI: 6.508)
    9.Shengnan Liu#, Yang Du#, He Ma*, Qian Liang, Xu Zhu*, Jie Tian*(2019). Preclinical comparison of regorafenib and sorafenib efficacy for hepatocellular carcinoma using multimodality molecular imaging. Cancer Letters. 2019 Jul 1;453:74-83. (2019 SCI: 6.508)
    10.Qian Liang#, Lingxin Kong#, Yang Du*, Xu Zhu*, Jie Tian*(2019). Anti-tumorigenic and -angiogenic efficacy of apatinib in liver cancer evaluated by multimodality molecular imaging. Experimental and Molecular Medicine. (2019)51:76. DOI : 10.1038/s12276-019-0274-7. (2019 SCI: 4.743)
    11.Yang Du#, Yinhua Jin#, Wei Sun, Junjie Fan, Jianjun Zheng*, Jie Tian*(2018). Advances in Molecular Imaging of Immunotherapeutic Targets in Breast Cancer: Current and Future Prospect. European Radiology. 2018 Nov 30. doi: 10.1007/s00330-018-5814-3. (2019 SCI: 3.962)
    12.Li Li, Yang Du*, Dehui Xiang, Liang Chen, Zhifeng Shi, Jie Tian*, Xinjian Chen*, (2018). Prediction of the anti-glioma therapeutic effects of temozolomide through the in vivo molecular imaging of the MMP expression. Biomedical Optics Express. 2018 Jun 20;9(7):3193-3207. (2019 SCI: 3.910)
    13.Ye J, Du Y, An Y, Chi C, Tian J*(2014). Reconstruction of fluorescence molecular tomography via a nonmonotone spectral projected gradient pursuit method. J Biomedical Optics. 2014 Dec 1;19(12):126013. (2019 SCI: 2.555)
    14.Yang Du+, Kelong Fan+, Hejun Zhang+, Li Li, Peixia Wang, Jiuyang He, Shigang Ding*, Xiyun Yan*, Jie Tian* (2018). Endoscopic molecular imaging of early gastric cancer using fluorescently labeled human H-ferritin. Nanomedicine. 2018 Oct;14(7):2259-2270. (2019 SCI: 5.570) 
    15.Du Y, Yang M, Lee S, Behrendt CL, Hooper LV, Saghatelian A, Wan Y. (2012). Maternal western diet causes inflammatory milk and TLR2/4-dependent neonatal toxicity. Genes and Development. Genes Dev. 2012 Jun 15;26(12):1306-11. (2019 SCI: 8.990)

     

    参加国际会议及相关报告:
    1.Haoxuan Ni1, Jinzuo Ye1, Dehui Xiang, Yang Du*, Xinjian Chen*, Jie Tian* (2018). A fast reconstruction algorithm for fluorescence molecular tomography via Multipath Subspace Pursuit method. SPIE Medical Imaging. 大会分会口头报告,2018年2月, 美国
    2.Li Li1, Jinzuo Ye1, Yang Du*, Xinjian Chen*, Jie Tian* (2018). Evaluation of chemotherapeutic response of temozolomide in orthotopic glioma using bioluminescence tomography. SPIE Medical Imaging,大会分会口头报告,2018年2月, 美国
    3.Yang Du, Jie Tian “A DNA Origami assembled with QD655 and gold nanorod working as a novel nanoprobe for fluorescence and optoacoustic dual modality imaging in 4T1 mammary tumor model” World Molecular Imaging Congress, 大会分会口头报告,2017年9月, 美国
    4.Yang Du,“The application of molecular imaging on oncology drug development”, Korea Society of Molecular Imaging Congress,大会分会口头报告, 2017年8月25, 韩国
    5.Qian Liang1, Jinzuo Ye1, Yang Du*, Chongwei Chi, Jie Tian* (2017). Evaluation of the anti-neoplastic effect of sorafenib on liver cancer through bioluminescence tomography. SPIE Medical Imaging. 大会分会口头报告,2017年2月, 美国
    6.Yang Du, Jie Tian. Synergistically improved antitumor treatment effects of PD-1 adjuvant immunotherapy after surgery in 4T1 breast tumor mouse model. AACR New Horizons in Cancer Research Conference. 2016年11月,中国AFLAC-supported Travel Awards
    7.Yang Du, Ting sun, Huadan Xue, Jie Tian. Infra Red Dye labeled programmed death 1 (PD-1) as a novel probe for fluorescence molecular imaging and image-guided intraoperative surgery in 4T1 breast tumors. Asian Oceanian Congress of Radiology, 大会分会口头报告,2016年8月,中国
    8.Yang Du, Qiao Jiang, Qian Zhang, Baoquan Ding, Jie Tian* “AS1411 aptamer guided QD655 labeled DNA Origami working as a novel nanoprobe for fluorescence molecular imaging in breast tumor mouse model” World Molecular Imaging Congress, 大会分会口头报告,2015年9月, 美国
    9.Yang Du, Nicolas Beziere, Qian Zhang, Dong Peng, Ntziachristos Vasilis, Jie Tian* “The gold nanorods decorated with DNA Origami working as a novel photoacoustic imaging probe in 4T1 breast tumor model” World Molecular Imaging Congress, 大会分会口头报告,2014年9月, 韩国
    10.Yang Du,“Application of Molecular Imaging Technology in Tumor Study”, Japanese Society of Molecular Imaging,大会分会口头报告, 2013年5月, 日本

     

    承担及参与项目:
    1.国家自然基金委面上项目《针对早期乳腺肿瘤和微小转移的新型磁纳米粒子成像研究》,2019-2022年度,课题负责人
    2.国家自然基金委面上项目《针对肿瘤相关巨噬细胞在乳腺肿瘤发展中分布和作用的分子影像学研究》,2015-2018年度,课题负责人
    3.永利科学院科研装备研制项目“小动物光学和光声断层多模融合分子影像设备”,2014-2015年度,课题负责人
    4.国家科技部重大科学研究计划“973青年科学家”项目《多模态医学影像技术在视网膜疾病的发生发展及视网膜组织工程修复中的应用》,2014-2018年度,课题主要参与人
    5.国家科技部重大科学研究计划“973项目”《脑胶质瘤精准诊疗技术的关键科学问题研究》,2015-2019年度,课题主要参与人
    6.北京市科委“生命科学领域前沿技术培育”专项 “基于DNA纳米结构的多模态分子影像探针”, 2016-2018年度,合作课题负责人
    7.北京市科技新星计划交叉学科合作课题“基于肿瘤分子影像技术中药调控乳腺癌作用评价体系关键方法研究”,2017-2018年度,

     

    获得荣誉:
    1.获得2017年在世界分子影像大会(World Molecular Imaging Congress,WMIC) 颁发的Molecular Imaging Scholar Award
    2.获得2015年世界分子影像大会(World Molecular Imaging Congress,WMIC) 颁发的Molecular Imaging Scholar Award
    3.2019年发表在Journal of Materials Chemistry B上的论文被评为2019 Journal of Materials Chemistry B Hot Papers
    4.2015年发表在Journal of Materials Chemistry B上的论文被评为2015 Journal of Materials Chemistry B Hot Papers
    5.2015年发表在Small期刊的论文被Wiley Material Views评为2015年Small热点文章Top 10
    6.2013年获得日本分子影像协会(Japanese Society of Molecular Imaging Conference)颁发的Travel Award
    7.2012年8月发表在Nature Communications上工作被Nature Communications作为研究亮点Research Highlight

    社会任职:
    研究方向:
    承担科研项目情况:
    代表论著:
    获奖及荣誉:
XML 地图 | Sitemap 地图